Dermatological changes are among the earliest visible indicators of immune activity.

Rashes in individuals living with HIV generally fall into three distinct categories:
3 Types of Skin Manifestations

1. Acute HIV Seroconversion Rash
When it occurs: 2 to 4 weeks after initial exposure during acute infection.
Appearance: A flat or slightly raised red area (maculopapular rash) usually appearing on the trunk, chest, or face, accompanied by fever, sore throat, and swollen lymph nodes.

2. Opportunistic Skin Conditions
Seborrheic Dermatitis: Red, scaly patches on the scalp, face, and chest.
Herpes Zoster (Shingles): Painful, fluid-filled blister bands following nerve pathways.
Molluscum Contagiosum: Small, firm, dome-shaped skin bumps.
Note: These conditions resolve rapidly as ART restores CD4 cell counts.

3. ART Medication Hypersensitivity Rash
Some individuals experience a mild drug rash during the first 1 to 2 weeks of starting a new ART drug.
⚠️ Warning: If a rash is accompanied by fever, mucosal blistering (in eyes or mouth), or facial swelling, seek immediate medical attention to rule out severe hypersensitivity reactions (e.g., Stevens-Johnson Syndrome).

Have a skin concern evaluated by our specialists at HIV Care India. Visit www.hivcareindia.com.


Aug 4th, 2026 2:35 AM